Indication

Renvela® (sevelamer carbonate) is used to control phosphorus levels in adults and children 6 years of age and older with chronic kidney disease (CKD) on dialysis.

Important Safety Information

• Do not use Renvela if you have a history of bowel obstruction or if you are allergic to sevelamer carbonate, sevelamer hydrochloride or to any of the ingredients in Renvela.
• Talk to your doctor if you have had difficulty swallowing or swallowing disorders; or if you have had digestive tract surgery or other digestive disorders, including severe constipation.
• The most frequently occurring side effects with Renvela tablets include nausea and vomiting.
• Side effects with Renvela powder taken three times a day are similar to those reported for Renvela tablets.
• The most common side effects with sevelamer include vomiting, nausea, diarrhea, indigestion, abdominal pain, flatulence, and constipation.
• Cases of itching, rash, fecal impaction and, less commonly, slow bowel activity, bowel obstruction, and bowel perforation have been reported.
• Uncommon cases of difficulty swallowing the Renvela tablet have been reported. Talk to your doctor if you have difficulty swallowing medicines in tablet form. Renvela for oral suspension may be considered by your doctor if you have a history of difficulty swallowing.
• Your doctor should monitor your bicarbonate and chloride blood levels.
• Reduced vitamins D, E, and K (clotting factors) and folic acid blood levels may be followed by your doctor.
• Talk to your doctor when taking Renvela with other medications.
• Promptly contact your doctor if you experience severe abdominal pain, new or worsening constipation, or other severe intestinal symptoms while on Renvela.
• Take Renvela with meals and adhere to your prescribed diet.

Please see full Prescribing Information.

If you are a patient experiencing problems with a Sanofi US product while participating in the Renvalue Copay Program, please call Sanofi US at 1-866-257-4605